Barely Significant
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Siponimod treatment response shows partial BDNF dependency in multiple sclerosis models.

Sci Rep · 2024 · PMC11294562 · PMID 39090252

2
hedged sentences
0.1000
closest p · 2.0× alpha
0.1000
boldest claim

The sentences

showed a trendp = 0.1so close (0.05 < p ≤ 0.1)
RIPK3 transcription showed a trend towards elevation in neurons in the BDNF ko group despite siponimod administration (p = 0.1 for BNDF ko ctrl vs.

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a small trendno p-value reported
In this setup, we did not see significant changes, although there was a small trend suggesting that conditioned media from WT EAE splenocytes has harmful effects on DRGs (Fig. 5 e).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.