Valproic acid use is associated with diminished risk of contracting COVID-19, and diminished disease severity: Epidemiologic and in vitro analysis reveal mechanistic insights.

As can be seen in Fig 7A , VPA, DHA and the combination of VPA+DHA all have substantial inhibitory activity against SARS-CoV2 at the doses tested (treated vs nontreated, p<0.001), with preincubation by 24 hours dropping the viral inhibitory effect from 20% to less than 10% though this did not reach statistical significance because of the low n (i.e., more than 50% reduction, p = 0.145, n = 3, two tailed t-test).

also in 111,027 other papers