No evidence of genetic causation between iron and infertility: a Mendelian randomization study.

Our analysis revealed that serum iron tended to show a negative causal association with female infertility; however, although the MR-Egger analysis did not reach statistical significance ( p = 0.116, se = 0.108), IVW ( p = 0.005, se = 0.066), weighted median ( p = 0.011, se = 0.075), and weighted mode ( p = 0.019, se = 0.078) analyses consistently indicated a negative causal association between serum iron and female infertility ( Table 1 ; Figure 2A ).

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