The ORR was higher in former smokers compared to never smokers (OR 2.10, 95% CI 1.40-3.15; P < .001) while it did not reach statistical significance between current and never smokers (OR 1.71, 95% CI 0.98-2.98; P = .06).
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Impact of smoking status on clinical outcomes in patients with metastatic renal cell carcinoma treated with first-line immune checkpoint inhibitor-based regimens.
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0.0600
0.0600