Unraveling the role of toxin-antitoxin systems in <i>Burkholderia pseudomallei</i>: exploring bacterial pathogenesis and interactions within the HigBA families.

Although there is not a total correlation in all the tested conditions for all the strains, and considering the lack of knowledge about how those systems impact the bacteria viability ( 13 ), there is a clear trend that allows establishing a generalized inverse relationship between the bacterial formation of persisters in response to antimicrobial treatment and its ability to form biofilm under the same antibiotic exposure.

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