Modulation of riboflavin biosynthesis and utilization in mycobacteria.

Although ATc-dependent knockdown of ribG or ribF did not reach statistical significance in their corresponding hypomorphs under the conditions tested, the survival of Mtb _ribG and Mtb_ ribF was, nonetheless, impaired under the conditions used to assess growth and survival (Fig.

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Transcriptional silencing of ribA2 , ribH, or ribC was specific, showing highly significant knockdown of the cognate gene.

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