Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.

Mol Neurodegener · 2024 · PMC11302177 · PMID 39107789

Europe PMC DOI

hedged sentences

0.0890

closest p · 1.8× alpha

0.0890

boldest claim

The sentences

approaching significancep = 0.089so close (0.05 < p ≤ 0.1)

SNCA was notably increased in all three LB disorders, reaching significance in PD ( p = 0.00021, log 2 Δ = 0.15) and PDD ( p = 1.51E-06, log 2 Δ = 0.17) and approaching significance in DLB ( p = 0.089, log 2 Δ = 0.12).

also in 1,607 other papers

highly significantno p-value reported

Compared to low-amyloid LBD cases, these P-M10 markers demonstrated large, highly significant fold-change elevations in those with high-amyloid LBD and were even more elevated in the UPenn AD cases (Fig. 6 B-C).

also in 82,236 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.