Evaluation of Efficacy and Safety in First-Line Treatment Methods for Extensive-Stage Small Cell Lung Cancer: A Comprehensive Comparative Study of Chemotherapy, Targeted Therapy Combined With Chemotherapy, and Immunotherapy Combined With Chemotherapy.

Compared to chemotherapy, immunotherapy combined with chemotherapy significantly improved ORR ( p = 0.007), and targeted therapy combined with chemotherapy showed a trend towards increased ORR, although the difference was not statistically significant ( p = 0.069) (Figure 5 ). 3.5 Single‐Factor Subgroup Analysis A single‐factor subgroup analysis was conducted on various factors between the chemotherapy group and the targeted therapy group (Figure 6 ).

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