Comparative In Vitro Study between Biocompatible Chitosan-Based Magnetic Nanocapsules and Liposome Formulations with Potential Application in Anti-Inflammatory Therapy.

Thus, according to the Tukey multiple comparison test, significant differences regarding the decrease in EA.hy296 endothelial cell viability were reported between the minimum and maximum concentrations studied, after 24 h of treatment, in the case of all liposomes tested ( Figure 16 ), except the CLDM2CP-1 variant, where insignificant or weakly significant decreases in cell viability were recorded (* p ≤ 0.05 and ** p ≤ 0.01).

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The p -value for drug concentration has a very small value, demonstrating that the concentration of the capsules has a highly significant influence on cell viability.

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However, these interactions are either marginally significant or not significant at other time points, indicating that their effects are both cell-specific and time-dependent.

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