The IVW method meta-analyzed SNP-specific Wald estimates using random effects to obtain the final estimate of the causal effect ( Burgess et al., 2019 ), which was reported in beta (β) value with standard error for continuous outcomes and odds ratio (OR) with a 95% confidence interval (CI) for binary outcomes; P -values < 0.05 were considered nominally significant.
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Investigating the association between gut microbiome and aortic aneurysm diseases: a bidirectional two-sample Mendelian randomization analysis.
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