Antibiotic resistance gene dynamics in the commensal infant gut microbiome over the first year of life.

However, there was also a highly significant overall temporal progression in ARG composition, both when looking at the data set as a whole (R 2 = 0.05, p < 0.001, Fig. 1 d), and when looking at each of the twelve infants individually (p < 0.01 for all tests).

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These correlations were statistically significant for nine infants, marginally significant for ID8 and 12, and non-significant for ID6 (Table 3 ) where hardly any E. coli was observed (Fig. 5 ).

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Unlike for ARGs, we did not see a significant trend in VF diversity (Fig.

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