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Valproic acid targets IDH1 mutants through alteration of lipid metabolism.

NPJ Metab Health Dis · 2024 · PMC11321993 · PMID 39149696

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The 2HG content in hemizygous IDH1 MT cell line BT142 was approximately double that of the IDH1 WT cell line but the difference did not reach statistical significance.

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