Barely Significant
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Circulating interleukin-8 and osteopontin are promising biomarkers of clinical outcomes in advanced melanoma patients treated with targeted therapy.

J Exp Clin Cancer Res · 2024 · PMC11325673 · PMID 39143551

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a clear trendno p-value reported
We did not observe a clear trend in cytokine levels across the different stages.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.