nearly significantP =0.07
In addition, the result of multivariate analysis (Appendix 3, Supplemental Digital Content 3, http://links.lww.com/JS9/C702 ) showed that laparoscopy was inferior to open surgery, and the effects were nearly significant (HR: 1.53, 95% CI: 0.97–2.39, and P =0.07 for the OS; HR: 1.45, 95% CI: 0.98–2.15, and P =0.06 for the DFS).