an increasing trendp < 0.001
In the participants aged under 60 years old, an increasing trend was found in WCCI ( p value for trend: <0.001) and reach a maximum of 1.2 (95% CI, [0.7, 1.8], p < 0.001; Fig. 3b ; Supplementary Table 3 ) when taking training for 6 days per week.