The association analysis excluding these cohorts shows the ε2 SNV (rs7412, P = 1.23 × 10 –12 , β = 0.70, MAF = 0.06) remained genome-wide significant and ε4 SNV (rs429358, P = 0.02, β = -0.16, MAF = 0.14) was nominally significant (Table S4, Table S5).
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Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy.
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