highly significantp = 2 × 10 −5
For the U-87 MG glioblastoma cell line, on which the present study was focused and for which correspondingly more experiments were performed, the enhancement was statistically highly significant ( p = 2 × 10 −5 ).
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First independent validation of the proton-boron capture therapy concept.
2
0.0000
0.1250
The sentences
Due to biological variabilities and the low number of independent experiments (in particular at the highest dose), the data and consequently the reported LQ coefficients possess large uncertainties, and the observed boron enhancement did not reach statistical significance ( p = 0.125).