Furthermore, although differences did not reach statistical significance, higher age at onset was observed in NCH subjects compared to CH T1D subjects (8.5 vs. 7.4 years), as well as a more elevated percentage of DKA at onset in NCH compared to CH (38.5% vs. 26%).
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Next-generation sequencing reveals additional HLA class I and class II alleles associated with type 1 diabetes and age at onset.
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