Sintilimab in combination with stereotactic body radiotherapy and granulocyte-macrophage colony-stimulating factor in metastatic non-small cell lung cancer: The multicenter SWORD phase 2 trial.

Meanwhile, a higher level of circulating IL-8, as well as a lower level of exosomal PD-L1, in the pre-SBRT and post-SBRT blood samples, was associated with the improved PFS and OS, although the association between circulating IL-8 in the pre-SBRT blood samples and OS did not reach statistical significance (Supplementary Fig. 2 ).

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