Effects of dynamic versus static parameter-guided fluid resuscitation in patients with sepsis: A randomized controlled trial.

This assumption corresponds to the study findings from Lanspa, et al., which showed that IVC collapsibility index threshold of ≥50% had a fair positive predictive value (75%) and a good negative predictive value (80%) for prediction of fluid responsiveness, although this did not reach statistical significance (p = 0.09). 31 Theoretically, patients with adequate fluid volume administration can likely maintain macrovascular and microvascular targets, and minimize duration of shock without excessive dose of vasopressors, resulting in fewer complications from prolonged shock or high dose of vasopressors. 40 – 42 However, patients in the dynamic IVC measurement group did not achieve more macrovascular or microvascular target(s) in 6 h than those in the other group in our study.

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