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Synthesis and Structure Optimization of Star Copolymers as Tunable Macromolecular Carriers for Minimal Immunogen Vaccine Delivery.

Bioconjug Chem · 2024 · PMC11342300 · PMID 39081220

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a clear trendno p-value reported
Furthermore, there was a clear trend between increasing arm M n and increased antibody responses with the star copolymers with 80 kg·mol –1 arms ( V2 and V4 ) inducing antibody titers that were greater than 10-fold higher than the star copolymers with 10 kg·mol –1 arms ( V1 and V3 ) and nearly 100-fold and statistically significantly higher than background levels observed in naïve animals.

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