An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals.

Of the remaining analyses of the sub-populations, when pregnant women were excluded, seven were showing a decreasing trend or no change (7/12 EE), whilst five showed an increasing trend (5/12 EE; Figure 5 ; Suppl File 2.4) [ 71 ].

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The majority of further sub-analyses in the general population showed a trend to towards an increase in risk of asthma with phthalate metabolites when restricted to postnatal assessment and also in adults only (13/15 EE; Figure 9 ; postnatal only, data not plotted; Suppl File 2.8) [ 90 ]; a significant association was observed for postnatal exposure to MBzP ( Figure 9 ; Suppl File 2.8) [ 90 ].

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