Systemic and cerebro-cardiac biomarkers following traumatic brain injury: an interim analysis of randomized controlled clinical trial of early administration of beta blockers.

The mean IL-6 levels at baseline, after 24 and 48 h, were significantly higher in Group 1 compared to the other groups, with a decreasing trend observed in Group 1 ( p = 0.001) and Group 2 ( p = 0.004).

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Interestingly, we observed a trend of decreasing IL-8 levels with lower GCS scores, although this elevation of IL-8 levels did not reach statistical significance.

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