However, surgical outcomes showed a trend, though not statistically significant (p-value 0.086), toward more extensive surgery (MRM) in patients with multiple clips.
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Comparative Evaluation of USG-Guided Single Tissue Marker Versus Multiple Tissue Marker Placements in Breast Malignancy Patients Undergoing Neoadjuvant Chemotherapy for Tumor Localization.
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Weak negative correlations between age and the number of clips, clipping to MG2, and clipping to operation suggest a slight trend toward younger patients requiring fewer clips and shorter follow-up times, though these were not statistically significant [ 17 ].