However, the expression of CXCL12 in the blood of SANFH was decreased, and the expression of PTH in osteoblasts under GC treatment was also decreased, while the PPR was increased and showed a trend of apoptosis [ 61 - 64 ].
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Differential Gene Expression and Immune Cell Infiltration in Patients with Steroid-induced Necrosis of the Femoral Head.
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It is estimated that there are around 80,000 individuals aged 12 or above in China affected by femoral head necrosis, with steroid-induced cases accounting for 51% and showing an increasing trend over the years.