<i>CD47</i> and <i>IFT57</i> Are Colinear Genes That Are Highly Coexpressed in Most Cancers and Exhibit Parallel Cancer-Specific Correlations with Survival.

Coexpression of CD47 and IFT57 mRNAs Is Intrinsic to Cancer Cells A highly significant positive correlation was also observed between CD47 and IFT57 mRNA expression across the 1156 cell lines in the Cancer Cell Line Encyclopedia (CCLE) [ 26 ] ( p = 4.6 × 10 −36 , Table 1 , Figure 1 d).

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Disease-free survival trended longer with higher CD47 but did not achieve significance ( p = 0.28, Figure 3 b).

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Low-grade glioma showed a similar decreased survival trend with higher CD47 mRNA that approached significance at a mean cutoff ( Table 1 , Figure 2 c) and became significant with cutoff optimization ( Figure S1d ) or when median expression was used as a cutoff ( Figure S2c ).

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