Factors Associated with Multi-Biologic Use in Psoriasis Patients at an Academic Medical Center and Review of Biologic Survival.

There was a trend towards significance on multivariate analysis ( P < .1) for initial presentation of PsO on the gluteal cleft and family history of psoriasis, such that initial presentation on the gluteal cleft was associated with using 3 or more biologic agents and family history was associated with using 1 biologic agent.

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There were many trends observed (association with multi-biologic failure with BMI, smoking, psoriasis severity) that did not reach statistical significance but that trended in the expected direction.

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