Mortality risk and mood stabilizers in bipolar disorder: a propensity-score-weighted population-based cohort study in 2002-2018.

The relationship between risperidone and a higher rate of mortality due to unnatural causes (relative to lithium) did not reach statistical significance in additional analyses on short exposure duration (<365 days, albeit remained significant for longer exposure of ≥1 and ≥2 years) and in the sensitivity analyses restricting to low MPR of other mood stabilizers and monotherapy (i.e., risperidone-only), precluding definitive conclusion in this respect.

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