The Emerging Role of Neurosteroids: Novel Drugs Brexanalone, Sepranolone, Zuranolone, and Ganaxolone in Mood and Neurological Disorders.

Cureus · 2024 · PMC11364262 · PMID 39219949

Europe PMC DOI

hedged sentence

0.1700

closest p · 3.4× alpha

0.1700

boldest claim

The sentences

did not reach statistical significancep = 0.17not close (p > 0.1)

Ganaxolone demonstrated a greater reduction in seizure frequency (-61.5%) compared to placebo (-24.0%) after the 17 weeks, but the difference did not reach statistical significance (p = 0.17).

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