Multi-omics analysis of Au@Pt nanozyme for the modulation of glucose and lipid metabolism.

Given the limited intervention period of 4 weeks for Au@Pt, any observed effects on body weight and organ weight may exhibit a decreasing trend; however, no statistically significant differences were identified.

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Heat map of dominant genera was analysed and the results showed that the number of dominant genera showed an increasing trend after Au@Pt treatment (Fig. 8 A).

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While, compared to the HFD group, the administration of Au@Pt showed a trend of reducing these indicators, but did not exhibit significant differences (Fig.

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