Effects of Nicotinamide Adenine Dinucleotide on Older Patients with Heart Failure.

Rev Cardiovasc Med · 2024 · PMC11366984 · PMID 39228487

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showed a trendno p-value reported

In our clinical trial, the SIRT1, SIRT3, and SIRT6 levels increased at the 2-week follow-up after medication, but over time, the concentration of exogenous supplemental NAD + gradually decreased in vivo and showed a trend of gradual decrease in the last two follow-up visits, which is also consistent with the metabolic process of intravenous drug use in the body.

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