Optimal target mean arterial pressure for patients with sepsis-associated encephalopathy: a retrospective cohort study.

The study showed that when MAP was < 81.5 mmHg, an increase in MAP was associated with a decrease in 28-day ICU and in-hospital mortality risks across all subgroups ( P < 0.05), except for patients with stage 0–1 acute kidney injury, where the association with in-hospital mortality did not reach statistical significance (HR: 0.90, 95% CI: 0.8–1.01, p = 0.07).

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