However, among those with any history of exacerbation, the difference in the frequency of moderate to very severe exacerbation between TEPS and those with COPD did not reach statistical significance (Self-report: 0.68 ± 0.87 exacerbations per year in TEPS versus 0.94 ± 1.25 in those with COPD [ P value from adjusted regression model = 0.391]; EHR-documented: 0.43 ± 0.27 exacerbations over three years in TEPS versus 0.64 ± 0.44 in those with COPD [ P value from adjusted regression model = 0.225]).
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Self-report underestimates the frequency of the acute respiratory exacerbations of COPD but is associated with BAL neutrophilia and lymphocytosis: an observational study.
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