Preliminary study of metabonomic changes during the progression of atherosclerosis in miniature pigs.

Although there was no notable disparity in the levels of HDL‐C between the two groups, the levels of TC and LDL‐C in the SA group showed a trend of increase compared to the NSA group, with certain time points showing significant differences (TC, at the fourth to eighth month, p < 0.05; LDL‐C, at the fourth, fifth, and eighth month, p < 0.05).

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Dynamic monitoring analysis highlighted 57 metabolites that exhibited an obvious trend of differential changes between two groups with the advance of time.

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