Telotristat ethyl, a tryptophan hydroxylase inhibitor, enhances antitumor efficacy of standard chemotherapy in preclinical cholangiocarcinoma models.

In pCCA SNU‐1196 xenografts, TE, GemCis, and NPT inhibited tumour growth, and the addition of TE to chemotherapy regimens showed a trend for synergistic effects (Figure 2I ).

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