Sexual dimorphism in hepatic PPAR alpha and CYP4a12a expression is associated with reduced development of drug-induced non-alcoholic steatohepatitis in female IL-33^-/- mice.

Specifically, at the 5-week timepoint, we found that CYP4v2 expression was higher in un-immunized and immunized males when compared to un-immunized and immunized females, respectively; however, these differences did not reach statistical significance ( Figures 2C , 3C ).

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