The results showed a trend of elevated TGF-β1 expression in the hearts of Dsg2 F536C/F536C mice before the onset of fibrosis (Additional file 1 : Fig.
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Hyperactivation of ATF4/TGF-β1 signaling contributes to the progressive cardiac fibrosis in Arrhythmogenic cardiomyopathy caused by DSG2 Variant.
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