The functional COL5A1 specificity protein 1 (Sp1) binding site polymorphism - BstUI RFLP C / T is positively correlated with tendon and ligament injuries, especially in Caucasian subjects. 14 15 Accordingly, a study on soccer players found that the T/T genotype of the COL5A1 BstUI RFLP showed a trend toward a higher severity of musculoskeletal injuries with respect to the individual carriers of the CC genotype. 15 The aim of this study was to correlate the COL5A1 gene BstUI RFLP and DpnII RFLP polymorphisms with ACLR in volleyball, basketball and soccer athletes.
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The COL5A1 Gene Allelic Combination and ACL Injury Risk in Team Sport: A Preliminary Report.
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