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Carrier-free cryptotanshinone-peptide conjugates self-assembled nanoparticles: An efficient and low-risk strategy for acne vulgaris.

Asian J Pharm Sci · 2024 · PMC11374989 · PMID 39246508

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Within the self-assembled NPs, CR exhibited the most potent downregulation effect against TNF-α ( P < 0.01 vs LPS), whereas the TNF-α levels in the CTS and CU groups, although reduced, did not reach statistical significance, possibly attributed to the low expression of TNF-α in HaCaT cells.

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