HSF1 is a prognostic determinant and therapeutic target in intrahepatic cholangiocarcinoma.

Concerning the mitochondrial bioenergetics, KRIBB-11 (10 μM) decreased basal and maximal mitochondrial respiration significantly compared with solvent alone in the two cell lines; a similar trend was detected for ATP production, although it did not reach statistical significance in HuCCT1 cells (Fig. 8 A, B).

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