In contrast, PIK3CD and TLR3 showed a trend positive correlation in schizophrenia, indicating possible suppression of PI3K-AKT signalling and potentially an enhanced inflammatory response in this group, in line with earlier PI3KCD findings 31 .
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Gene expression changes in Brodmann's Area 46 differentiate epidermal growth factor and immune system interactions in schizophrenia and mood disorders.
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