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MHC class I and II-deficient humanized mice are suitable tools to test the long-term antitumor efficacy of immune checkpoint inhibitors and T-cell engagers.

J Immunother Cancer · 2024 · PMC11381650 · PMID 39244214

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Tumor-infiltrating CD4 + T cells showed a tendency that did not reach statistical significance ( online supplemental figure 10D ).

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