Chemotherapy and programmed cell death protein 1/programmed death-ligand 1 inhibitor combinations for tyrosine kinase inhibitor-resistant, epidermal growth factor receptor-mutated non-small-cell lung cancer: a meta-analysis.

ESMO Open · 2024 · PMC11381989 · PMID 39168027

Europe PMC DOI

hedged sentences

0.0614

closest p · 1.2× alpha

0.0614

boldest claim

The sentences

borderline significantP = 0.0614so close (0.05 < p ≤ 0.1)

10 The interaction effect between PD-(L)1 and VEGF inhibitors was borderline significant for PFS ( P = 0.0614) in our meta-analysis, hence effect sizes were estimated separately according to the use of anti-VEGF therapy.

also in 11,409 other papers

did not reach statistical significanceno p-value reported

While patients with PD-L1 ≥50% treated with chemotherapy and nivolumab had the longest median PFS in the CheckMate-722 study, the results did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.