ISG15/GRAIL1/CD3 axis influences survival of patients with esophageal adenocarcinoma.

JCI Insight · 2024 · PMC11383178 · PMID 38781019

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0.0900

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0.0900

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showed a trendP = 0.09so close (0.05 < p ≤ 0.1)

Additionally, we performed immunohistochemical (IHC) staining of an EAC TMA ( n = 46) showing patients expressing ISG15 ( n = 40) showed a trend of correlation with poor OS ( P = 0.09) compared with nonexpressors ( n = 6; ~12% of all EACs) ( Figure 6, H and I , and Table 2 ), suggesting a critical role of ISG15 expression in EAC.

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