Unveiling microbial dynamics in lung adenocarcinoma and adjacent nontumor tissues: insights from nicotine exposure and diverse clinical stages via nanopore sequencing technology.

Although the P-value didn’t reach significance, we observed a notable trend towards elevated tumor microbiota abundance in the smoking cohort when compared to non-smokers ( Figure 5A ).

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Overall, the alpha diversity of the microbiota in the nicotine-exposed group surpassed that of the non-exposed group, even though the p-value did not reach statistical significance.

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