Evaluating the efficacy and safety of different neoadjuvant immunotherapy combinations in locally advanced HNSCC: a systematic review and meta-analysis.

Furthermore, the 15 studies that reported pCR rates (ranging from 16.7% to 68.2%) indicated that both the NIRT and NICT groups had higher pCR rates than the NI group, although this difference did not reach statistical significance (P=0.54, I 2 = 0%, Figure 2B ).

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