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Establishment of Reference Intervals for Bone Turnover Biomarkers in Healthy Populations in Northern China.

Int J Gen Med · 2024 · PMC11390834 · PMID 39268179

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an increasing trendno p-value reported
During the seasons, 25(OH)D serum levels showed an increasing trend from spring to summer, then a clear decreasing trend from summer to fall to the lowest levels in winter.

also in 63,971 other papers

showed a trendno p-value reported
OC, β-CTX and P1NP showed a trend of decreasing in spring to summer, and then further increased in fall and winter.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.