Similar results were reported by Myint et al., who did not show a statistical difference in MS but showed a trend toward worse disease-free survival with high GLS mRNA levels [ 26 ].
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Prostate Cancer's Silent Partners: Fibroblasts and Their Influence on Glutamine Metabolism Manipulation.
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The analysis identified several key pathways significantly enriched in our dataset, including metabolic pathways with highly significant gene enrichment in LNCaP co-cultured cells and several pathways influencing the extracellular matrix in CAF-co-cultured cells ( Figure S2B ).