Ranolazine Unveiled: Rediscovering an Old Solution in a New Light.

Furthermore, the synergistic effect of ranolazine when combined with class III antiarrhythmic drugs like amiodarone and dronedarone seems to be highly significant.

also in 132,142 other papers

The RAID trial, aiming to assess the efficacy of high doses of ranolazine (1 g BID) in a high arrhythmic risk population (ICD carriers in secondary prevention or those at high risk of VA based on baseline characteristics) with ischemic or nonischemic cardiomyopathy, did not reach statistical significance for its primary endpoint (occurrence of VT or VF requiring ICD therapy or death) despite a trend favoring ranolazine (34.1% vs. 39.4% in the ranolazine and placebo groups, respectively; p = 0.117) [ 36 ].

also in 111,027 other papers