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Structure-Aided Computational Design of Triazole-Based Targeted Covalent Inhibitors of Cruzipain.

Molecules · 2024 · PMC11396839 · PMID 39275072

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a clear trendno p-value reported
As shown in Figure S3a , a clear trend of more negative docking score values was found for the reference compounds exhibiting lower IC 50 , confirming the predictive power of the molecular docking protocol to identify bioactive poses and sort them according to their inhibitory potency.

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